Lactobacillus fermentum strain and composition for preventing or treating metabolic disease containing same

• Main Authors: YANG BO-KI, KANG CHANG-HO, ZHANG MINGHAO, BAEK NAM-SOO
• Format: Patent
• Language: Chinese; English
• Published: 30.09.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FODDER; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The present invention relates to a novel Lactobacillus fermentum strain (preservation number KCTC 14105BP) and a composition for preventing or treating metabolic diseases comprising the same. The Lactobacillus fermentum according to the present invention can inhibit fat accumulation in white adipose tissue and increase the amount of anti-inflammatory cells. The lactobacillus fermentum strain shows an excellent blood glucose improving effect, and especially can reduce the fasting blood glucose level. The lactobacillus fermentum strain can improve glucose tolerance and increase insulin sensitivity, thereby effectively improving insulin resistance. In addition, the lactobacillus fermentum strain can control the concentration of metabolic hormones and fat factors in blood. Thus, the Lactobacillus fermentum strain can be usefully used in the prevention and treatment of metabolic diseases such as obesity. 本发明涉及一种新型发酵乳杆菌菌株(保藏号KCTC 14105BP)和包含该菌株的用于预防或治疗代谢疾病的组合物。根据本发明的发酵乳杆菌可以抑制白色脂肪组织中的脂肪堆积并增加抗炎细胞的量。发酵乳杆菌菌株表现出优异的血糖改善作