Lactobacillus plantarum strain and composition for preventing or treating metabolic disease containing same

• Main Authors: YANG BO-KI, KANG CHANG-HO, ZHANG MINGHAO, BAEK NAM-SOO
• Format: Patent
• Language: Chinese; English
• Published: 30.09.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FODDER; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The present invention relates to a novel Lactobacillus plantarum strain and a composition for preventing or treating metabolic diseases comprising the same. The lactobacillus plantarum (the preservation number is KCTC 14107BP) provided by the invention can effectively inhibit fat accumulation in white adipose tissues, brown adipose tissues and liver tissues. The lactobacillus plantarum strain shows an excellent blood glucose improving effect, and especially can reduce the fasting blood glucose level. The lactobacillus plantarum strain can improve glucose tolerance and increase insulin sensitivity, thereby effectively improving insulin resistance. In addition, the lactobacillus plantarum strain can control the concentration of metabolic hormones in blood. Therefore, the Lactobacillus plantarum strain can be usefully used for preventing or treating metabolic diseases. 本发明涉及一种新型植物乳杆菌菌株和包含该菌株的用于预防或治疗代谢疾病的组合物。根据本发明的植物乳杆菌(保藏号KCTC 14107BP)可以有效抑制白色脂肪组织、棕色脂肪组织和肝组织中的脂肪堆积。植物乳杆菌菌株表现出优异的血糖改善作用，特别是可以降低空腹血糖水平。植物乳杆菌菌株可改善葡萄糖耐