Farnesy transferase inhibitors having pyrrole structure and process for preparation thereof

本发明涉及对法尼转移酶表现出抑制活性的新的吡咯衍生物或其药用可接受的盐或异构体；涉及制备所说化合物的方法；并涉及含有所说化合物作为活性成分并结合药用可接受的载体的药物组合物如抗癌组合物等。 The present invention relates to a novel pyrrole derivative which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof; to a process for prepara...

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Bibliographic Details
Main Authors LEE HYUN-II, KOH JONG-SUNG, SHIN YOU-SEUNG
Format Patent
LanguageChinese
English
Published 26.05.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:本发明涉及对法尼转移酶表现出抑制活性的新的吡咯衍生物或其药用可接受的盐或异构体；涉及制备所说化合物的方法；并涉及含有所说化合物作为活性成分并结合药用可接受的载体的药物组合物如抗癌组合物等。 The present invention relates to a novel pyrrole derivative which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof; to a process for preparation of said compound; and to a pharmaceutical composition such as anti-cancer composition, etc. comprising said compound as an active ingredient together with pharmaceutically acceptable carrier.
Bibliography:Application Number: CN20008006149