Royal jelly extract as well as extraction method and application thereof

• Main Authors: DENG JUN, CAO ZHIMEI, TAN ZHENYOU
• Format: Patent
• Language: Chinese; English
• Published: 27.09.2022
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The invention discloses a royal jelly extract as well as an extraction method and application thereof, the extraction method comprises the following steps: S1, performing enzymolysis on royal jelly, performing ultrafiltration by using a 2KD-3KD filter membrane, and then performing ultrafiltration by using a 9KD-10KD ultrafiltration membrane to obtain filtrate; and S2, adjusting the pH value of the filtrate, and purifying by using anion exchange resin to obtain the royal jelly extract. The extraction method can be used for extracting the royal jelly extract with the molecular weight of 5KD-9KD, and is simple, easy to operate and suitable for industrial popularization and application. The royal jelly extract has excellent skin tightening, anti-wrinkle and anti-inflammatory effects, has excellent ROS (reactive oxygen species), TNF-alpha (tumor necrosis factor-alpha) and MMP-1 inhibition effects, and can increase the content of I-type collagen and elastin in the skin to keep the skin tight. 本发明公开了一种蜂王浆提取物及其提取方法和应