Bone repair foaming composite material and preparation method thereof

• Main Authors: ZHU YU, ZHAO YIYANG, CHEN ZONGJU, ZHANG YI, ZHANG XIUCHENG, YANG KEQING, YANG JINGLONG
• Format: Patent
• Language: Chinese; English
• Published: 20.09.2022
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

The invention relates to a biodegradable composite material taking hydroxyapatite and nano cellulose as reinforcement bodies and polylactic acid as matrix resin and a preparation method thereof, the foamed composite material comprises the following components in parts by weight: 20-80 parts of nano hydroxyapatite, 5-30 parts of surface modified nano cellulose, 10-50 parts of polylactic acid, 1-15 parts of a foaming agent, 0.05-0.50 part of an activating agent and 0.1-0.5 part of an antioxidant, 1-5 parts of a heat stabilizer and 10-50 parts of a biodegradation accelerator. According to the implementation scheme, a reinforcing material nano-cellulose is added into nano-hydroxyapatite, polylactic acid with good biocompatibility is used as a matrix, a foaming agent and other auxiliaries are added at the same time, and the composite material with good biocompatibility, biodegradability and pore connectivity is prepared through foaming. The nano-crystalline cellulose/hydroxyapatite/polylactic acid composite materi