Norcantharidin nanostructure lipid carrier with tumor targeting property and preparation method of norcantharidin nanostructure lipid carrier
The invention discloses a norcantharidin nanostructure lipid carrier with tumor targeting and a preparation method thereof, and belongs to the field of pharmaceutical preparations. The invention relates to a norcantharidin nanostructure lipid carrier with tumor targeting property. The norcantharidin...
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Main Authors | , , , , |
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Format | Patent |
Language | Chinese English |
Published |
16.09.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The invention discloses a norcantharidin nanostructure lipid carrier with tumor targeting and a preparation method thereof, and belongs to the field of pharmaceutical preparations. The invention relates to a norcantharidin nanostructure lipid carrier with tumor targeting property. The norcantharidin nanostructure lipid carrier is prepared from the following raw material components in parts by weight: 0.1 to 6 parts of norcantharidin, 5 to 15 parts of polyethylene glycol-400, 8 to 16 parts of polyoxyethylated castor oil, 20 to 50 parts of ethyl oleate, 0.4 to 2 parts of tripalmitin, 1 to 5 parts of phospholipid, 2 to 5 parts of glyceryl monostearate, 1 to 5 parts of tween-80 and 72 to 308 parts of water phase. The norcantharidin nanostructure lipid carrier with tumor targeting improves bioavailability, keeps effective blood concentration for a long time, effectively increases targeting in tumor tissues, reduces toxic and side effects, and can effectively solve the problems that an existing norcantharidin deliv |
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Bibliography: | Application Number: CN202210705238 |