Synthetic method and application of organic aluminum hydrogen reagent
The invention discloses a synthesis method and application of an organic aluminum hydrogen reagent, and the synthesis method comprises the following steps: dissolving an organic aluminum chloride compound containing a strong electron-withdrawing substituent group in an organic solvent in an inert ga...
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Main Authors | , , |
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Format | Patent |
Language | Chinese English |
Published |
13.09.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The invention discloses a synthesis method and application of an organic aluminum hydrogen reagent, and the synthesis method comprises the following steps: dissolving an organic aluminum chloride compound containing a strong electron-withdrawing substituent group in an organic solvent in an inert gas atmosphere, adding a metal hydride at-78 DEG C to-20 DEG C, continuously stirring for 0.5-1 hour, then heating to 10-50 DEG C, continuously reacting for 12-72 hours, and cooling to room temperature to obtain the organic aluminum hydrogen reagent. Filtering and recrystallizing to obtain an organic aluminum hydrogen reagent containing a strong electron-withdrawing substituent group; according to the invention, the metal hydride is used as a reducing agent, and meanwhile, the synthesis of the organic aluminum hydrogen reagent containing a strong electron-withdrawing substituent group is realized by controlling reaction conditions, so that high yield and high purity can be obtained, and the yield can be up to 62%; me |
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Bibliography: | Application Number: CN202210580187 |