Methods and nucleic acids for analyzing cell proliferative disorders

• Main Authors: LESCHE RALF, SLEDZIEWSKI ANDREW, DISTLER JUERGEN, SONG XIAOLING, HILDMANN THOMAS, TETZNER, REMO, LOFTON-DAY CATHY, MODEL FABIAN, SCHUSTER MATTHIAS
• Format: Patent
• Language: Chinese; English
• Published: 19.08.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to methods and nucleic acids for analyzing cell proliferative disorders. The present invention provides methods, nucleic acids and kits for detecting, or for detecting and differentiating liver cell proliferative disorders or for detecting and differentiating colorectal cell proliferative disorders. Particular aspects disclose and provide genomic sequences whose methylation patterns have important uses for improved detection and differentiation of such disorder species, thereby enabling improved diagnosis and treatment of patients. 本发明涉及分析细胞增殖性病症的方法和核酸。本发明提供用于检测，或用于检测和区分肝细胞增殖性病症或用于检测和区分结肠直肠细胞增殖性疾病的方法、核酸和试剂盒。具体方面公开和提供基因组序列，其甲基化模式对于所述病症种类的改进的检测和区分有重要的用途，由此使得对患者的改进的诊断和治疗成为可能。