Resveratrol hydrophilic gel skeleton sustained release tablet and preparation method thereof

• Main Authors: SONG LIHUA, ZHANG CHUNGANG, WU YANAN, YU CHENCHEN, ZHENG JINPING, HE YANBIN, LI JUNBO
• Format: Patent
• Language: Chinese; English
• Published: 19.08.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides a resveratrol hydrophilic gel skeleton sustained release tablet and a preparation method thereof, and relates to the technical field of medicines. The resveratrol hydrophilic gel skeleton sustained-release tablet provided by the invention is prepared from the following components in percentage by mass: 1 to 25 percent of resveratrol, 25 to 40 percent of hydrophilic carrier, 10 to 50 percent of sustained-release material and the balance of filler. The resveratrol hydrophilic gel matrix sustained-release tablet provided by the invention has the characteristics of high dissolution rate and sustained release, is stably released in vivo, can maintain effective blood concentration for a long time, and reduces the administration frequency. Besides, the resveratrol hydrophilic gel skeleton sustained-release tablet also has relatively high stability, and the content of resveratrol in the sustained-release tablet is basically unchanged under the conditions of high temperature, high humidity, inte