Recombinant vibrio natriticus for producing hydroxytyrosol and application of recombinant vibrio natriticus

• Main Authors: CUI XIAOYI, TENG XIN, FAN BING, JIAN YIMIN, TAN CHANG, ZONG ZHEN
• Format: Patent
• Language: Chinese; English
• Published: 09.08.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention relates to the technical field of bioengineering, in particular to a recombinant vibrio natriureticus for producing hydroxytyrosol and application of the recombinant vibrio natriureticus. The invention provides a novel application of vibrio natriticus in production of hydroxytyrosol. The vibrio natriticus engineering bacterium obtained through transformation can be used for whole-cell catalytic synthesis of hydroxytyrosol, can efficiently promote accumulation of hydroxytyrosol, and can also be used as a chassis bacterium for constructing a hydroxytyrosol production strain. According to the method for producing the hydroxytyrosol based on the vibrio natriureticus, the production period of the hydroxytyrosol can be shortened while the yield of the hydroxytyrosol is guaranteed, the yield of the hydroxytyrosol is increased, and the removal difficulty of downstream endotoxin is reduced. 本发明涉及生物工程技术领域，具体涉及一种生产羟基酪醇的重组需钠弧菌及其应用。本发明提供了需钠弧菌在生产羟基酪醇中的新用途。经改造获得的需钠弧菌工程菌可用于全细胞催化合成羟基酪醇，并能够高效促进羟基酪醇的积累，还可作为底盘菌用于构建