Collagen composite solution for injection and preparation method thereof

• Main Authors: CHANG, HONG-SUNG, BAO LIUJUN, XU SONGCHENG
• Format: Patent
• Language: Chinese; English
• Published: 05.08.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The invention provides a collagen composite solution for injection and a preparation method thereof. The collagen composite solution for injection is prepared from the following components in percentage by mass: 0.1 to 0.6 weight percent of active collagen, 0.15 to 0.35 weight percent of acid-base amino acid, 0.0005 to 0.2 weight percent of composite nutrient substance, 0.01 to 0.2 weight percent of collagen stabilizer, 0.8 to 1 weight percent of sodium chloride and the balance of water. According to the collagen composite solution for injection, on the basis of maintaining a natural collagen molecular structure, the pH value of a system is controlled through the special acid-base amino acid, and the collagen stabilizer is introduced to improve the hydrophilicity of collagen molecules, so that the stability of the collagen molecules is improved; furthermore, the solubility and the stability of collagen molecules in the compounding process of the collagen molecules and small molecular nutrient substances under