Application of RHPS4 in preparation of medicine for inhibiting human pathogenic bacteria and medicine thereof

• Main Authors: WANG ZHANGQIAN, GAO CHAO, ZHANG SISHANG
• Format: Patent
• Language: Chinese; English
• Published: 08.07.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses application of RHPS4 in preparation of a medicine for inhibiting human pathogenic bacteria, and the whole name of the RHPS4 is 3, 11-difluoro-6, 8, 13-trimethyl-8H-quinolo [4, 3, 2-kl] acridine onium methyl sulfate salt. The invention further discloses a medicine for inhibiting the human pathogenic bacteria, and the active ingredient of the medicine comprises the 3, 11-difluoro-6, 8, 13-trimethyl-8H-quinolino [4, 3, 2-kl] acridine onium methyl sulfate salt, namely the 3, 11-difluoro-6, 8, 13-trimethyl-8H-quinolino [4, 3, 2-kl] acridine onium methyl sulfate salt. The 2, 3, 11-difluoro-6, 8, 13-trimethyl-8H-quinolino [4, 3, 2-kl] acridinium methyl sulfate salt disclosed by the invention can be used for effectively inhibiting the growth of staphylococcus aureus and pseudomonas aeruginosa. 本发明公开了RHPS4在制备抑制人类病原菌药物中的应用，所述RHPS4的全称为3,11-二氟-6,8,13-三甲基-8H-喹啉并[4,3,2-kl]吖啶鎓硫酸甲酯盐；本发明还公开了一种抑制人类病原菌的药物，所述药物的活性成分包括3,11-二氟-6,8,13-三甲基-8H-喹啉并[4,3,2-kl]吖啶鎓硫酸甲酯盐。3,11-二氟-6,8,13-三甲基-8H-喹啉并[4,3,2-kl]吖啶鎓硫酸甲酯盐能够