Application of SSH3 protein in prognosis prediction of cardia adenocarcinoma

• Main Authors: WANG LIDONG, MA SAI, WEI MENGXIA, FAN ZONGMIN, ZHONG KAN, LEI LINGLING, HU JINGFENG, HAN XUENA, SONG XIN, ZHAO XUEKE, XU RUIHUA
• Format: Patent
• Language: Chinese; English
• Published: 05.07.2022
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention belongs to the technical field of medical biology, and particularly discloses a marker SSH3 protein for predicting the prognosis of cardia adenocarcinoma and application of a detection reagent of the SSH3 protein in preparation of drugs for predicting the prognosis of the cardia adenocarcinoma. The SSH3 protein is in negative expression in normal epithelial tissues beside the cardia adenocarcinoma and has different degrees of positive expression in cardia adenocarcinoma tissues, and patients with the cardia adenocarcinoma with positive expression of the SSH3 protein are short in lifetime. By detecting the expression of the SSH3 protein in a tissue sample, the lifetime of a cardia adenocarcinoma patient can be effectively distinguished, so that a new way is provided for judging prognosis prediction of the cardia adenocarcinoma, and a reference basis is provided for clinical doctors to analyze the condition of the cardia adenocarcinoma. 本发明属于医药生物技术领域，具体公开了一种预测贲门腺癌预后的标志物--SSH3蛋白以及SSH3蛋白的检测试剂在制备预测贲门