Marker for screening colorectal stage II high-risk groups and application thereof

• Main Authors: LUO YANRAN, CHENG XUEXIN, LIAO YUCUI, YING HOUQUN, XIONG GANG
• Format: Patent
• Language: Chinese; English
• Published: 28.06.2022
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention belongs to the technical field of biomarkers, and discloses a marker for screening colorectal stage II high-risk groups and application of the marker, and the marker for screening colorectal stage II high-risk groups is FPR. FPR is the ratio of circulating fibrinogen to prealbumin. The value and efficacy of stage-II high-risk population predicted and identified by the ratio of fibrinogen to prealbumin are obviously higher than those of clinical characteristic parameters. The invention discloses the value of the ratio of fibrinogen to prealbumin as the marker for identifying colorectal cancer phase II recurrence high-risk groups for the first time. The method solves the problem of low efficiency of screening patients according to clinical characteristics, can obviously improve the efficiency of identifying real high-risk relapse patients, reduces the relapse and distant metastasis morbidity of real high-risk groups after chemotherapy treatment, greatly reduces the clinical treatment cost of real