Methods of administering beta7 integrin antagonists

• Main Authors: ANAND, BHARAT, TANG, MING, O 'BYRNE SEAN, STEFANICH ERIC, VISCH, J ¨ 1 RGEN, WILLIAMS MICHAEL
• Format: Patent
• Language: Chinese; English
• Published: 21.06.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to methods of administering beta7 integrin antagonists. The present invention provides methods of treating gastroenteritis disorders, such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease. The invention also provides methods of administering integrin [beta] 7 antagonists, such as anti-[ beta] 7 antibodies. Furthermore, the present invention provides specific dosing regimens, including dosing regimens comprising subcutaneous administration and administration using a self-injection device. 本发明涉及施用β7整联蛋白拮抗剂的方法。本发明提供治疗诸如包括溃疡性结肠炎和克隆病的炎性肠病的胃肠炎性障碍的方法。本发明还提供施用诸如抗-β7抗体的整联蛋白β7拮抗剂的方法。此外，本发明提供具体的给药方案，包括含有皮下施用和使用自注射装置的施用的给药方案。