一种用于肺顺应性可视化定量评价的快速磁共振成像方法

本发明公开了一种用于肺顺应性可视化定量评价的快速MRI方法，受试者根据设定的目标屏气压力分n次吸入超极化惰性气体完成吸气过程，每次吸气后屏气进行肺部气体MRI扫描；得到n组气道屏气压力、以及校正后的肺体积分布；对校正后的肺体积分布采用图像配准算法，获得配准到最小气道屏气压力下的肺体积分布；通过不同气道屏气压力下肺体积分布的点对点拟合，计算肺部顺应性分布，以及肺顺应性对不同方向的依赖系数R。本发明基于超极化惰性气体快速MRI对肺内气体进行直接成像，无电离辐射与放射性，扫描时间短，采样速度快，肺部体积计算准确，更适合在临床推广。 The invention discloses a rapid MR...

Full description

Saved in:
Bibliographic Details
Format Patent
LanguageChinese
Published 09.08.2024
Subjects
CALCULATING
COMPUTING
COUNTING
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
MEASURING
MEASURING ELECTRIC VARIABLES
MEASURING MAGNETIC VARIABLES
MEDICAL OR VETERINARY SCIENCE
PHYSICS
SURGERY
TESTING
Online AccessGet full text

Cover

More Information
Summary:本发明公开了一种用于肺顺应性可视化定量评价的快速MRI方法，受试者根据设定的目标屏气压力分n次吸入超极化惰性气体完成吸气过程，每次吸气后屏气进行肺部气体MRI扫描；得到n组气道屏气压力、以及校正后的肺体积分布；对校正后的肺体积分布采用图像配准算法，获得配准到最小气道屏气压力下的肺体积分布；通过不同气道屏气压力下肺体积分布的点对点拟合，计算肺部顺应性分布，以及肺顺应性对不同方向的依赖系数R。本发明基于超极化惰性气体快速MRI对肺内气体进行直接成像，无电离辐射与放射性，扫描时间短，采样速度快，肺部体积计算准确，更适合在临床推广。 The invention discloses a rapid MRI (Magnetic Resonance Imaging) method for visual quantitative evaluation of lung compliance, which comprises the following steps that: a subject inhales hyperpolarized inert gas for n times according to a set target breath-holding pressure to finish an inspiration process, and carries out lung gas MRI scanning by holding breath after inspiration each time; obtaining n groups of airway breath-holding pressures and corrected lung volume distribution; an image registration algorithm is adopted for the corrected lung volume distribution, and the lung volume distribution registered to the minimum airway breath-holding pressure is obtained; through point-to-point fitting of lung volume distribution under different airway
Bibliography:Application Number: CN202210280982