Detection method and application of beta-nicotinamide mononucleotide and related substances thereof

• Main Authors: ZHANG ZIJUAN, WU BOLONG, ZHANG JIALIN, YU SHUISHENG, YU MEI, FAN CHUNLIN
• Format: Patent
• Language: Chinese; English
• Published: 17.05.2022
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention belongs to the technical field of nuclear magnetic quantitative analysis and detection, and particularly relates to a detection method and application of beta-nicotinamide mononucleotide and related substances thereof. According to the detection method provided by the invention, a one-pot method can be used for detection, separation is not needed, six related compounds can be quantified at the same time, the detection time is short, and the efficiency is high. Besides, nuclear magnetic spectrum signal peaks of different compounds appear in groups and are single peaks, and the compounds can be judged to be non-to-be-detected compounds, so that false positive does not appear. Powerful technical support is provided for production, research and development, quality control, safety detection, market supervision and the like of subsequent NAD supplement related products. 本发明属于核磁定量分析检测技术领域，具体涉及一种β-烟酰胺单核苷酸及其相关物质的检测方法和应用。本发明提供的检测方法，可"一锅法"进行检测，无需分离，可同时对6种相关联的化合物进行定量，检测用时短、效率高。另外，不同的化合物的核磁谱图信号峰，均是成组地出现，单一出