Treatment of heart failure in human subjects

The present invention relates to oligonucleotides that are potent inhibitors of microRNA miR-132 and their use in medicine, in particular in the prevention or treatment of cardiac and/or fibrotic conditions in a human subject. 本发明涉及作为微小RNA miR-132的有效抑制剂的寡核苷酸及其在医学中的用途，特别是在预防或治疗人受试者的心脏和/或纤维化病症中的用途。...

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Bibliographic Details
Main Authors ALBRICH CHRISTIAN, HAUCK, WOLFGANG, BARTKAI STEPHEN, LAMPE SIEGFRIED, THUM THOMAS
Format Patent
LanguageChinese
English
Published 06.05.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to oligonucleotides that are potent inhibitors of microRNA miR-132 and their use in medicine, in particular in the prevention or treatment of cardiac and/or fibrotic conditions in a human subject. 本发明涉及作为微小RNA miR-132的有效抑制剂的寡核苷酸及其在医学中的用途，特别是在预防或治疗人受试者的心脏和/或纤维化病症中的用途。
Bibliography:Application Number: CN202080051186