Thio-oxindole derivatives

本发明涉及作为黄体酮受体激动剂的化合物或其药学上可接受的盐，它具有下示的通式(1)或(2)，其中取代基如文中定义；以及用这些化合物来诱导避孕或治疗与黄体酮有关的癌和腺癌。∴ 1. Technical Result Improvement of medicinal properties and increase in treatment efficiency. 2. Essence A compound of the formula (1) wherein R1-R5 and Q have the values indicated in the description or a pharmace...

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Bibliographic Details
Main Authors A. FENSOME, ZHANG PUWEN, M.C. KOKO
Format Patent
LanguageChinese
English
Published 31.03.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:本发明涉及作为黄体酮受体激动剂的化合物或其药学上可接受的盐，它具有下示的通式(1)或(2)，其中取代基如文中定义；以及用这些化合物来诱导避孕或治疗与黄体酮有关的癌和腺癌。∴ 1. Technical Result Improvement of medicinal properties and increase in treatment efficiency. 2. Essence A compound of the formula (1) wherein R1-R5 and Q have the values indicated in the description or a pharmaceutically acceptable salt thereof and their use for mammals to obtain the medicament for treatment carcinomas and adenocarcinomas of endometrium, ovary, mammary gland, colon or prostatitis, dysfunctional haemorrhage and menopause after substitution hormonotherapy 3. Field of Application Medicine.
Bibliography:Application Number: CN20008007133