Mifepristone capsule and preparation method thereof
The invention discloses a mifepristone capsule and a preparation method thereof. The mifepristone capsule comprises mifepristone, a solubilizer, an adhesive, an acidity regulator and a diluent. The preparation method of the mifepristone capsule comprises the following steps: firstly crushing mifepri...
Saved in:
Main Authors | , , , |
---|---|
Format | Patent |
Language | Chinese English |
Published |
22.04.2022
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The invention discloses a mifepristone capsule and a preparation method thereof. The mifepristone capsule comprises mifepristone, a solubilizer, an adhesive, an acidity regulator and a diluent. The preparation method of the mifepristone capsule comprises the following steps: firstly crushing mifepristone, and then mixing the crushed mifepristone with a solubilizer to obtain a mifepristone mixture containing the solubilizer; mixing the mifepristone mixture containing the solubilizer with an adhesive, an acidity regulator and a diluent to obtain a capsule content; and finally, filling the capsule content into an empty capsule to obtain the mifepristone capsule. The mifepristone capsule prepared by adding the self-made solubilizer has a very good slow-release effect in intestinal tracts, and the bioavailability can be remarkably improved.
本发明公开了一种米非司酮胶囊及其制备方法,其包括米非司酮,增溶剂,黏附剂,酸度调节剂,稀释剂。该米非司酮胶囊的制备方法为先将米非司酮粉碎,再将粉碎后的米非司酮与增溶剂混合,得到含有增溶剂的米非司酮混合物;再将含有增溶剂的米非司酮混合物与黏附剂、酸度调节剂、稀释剂混合得到胶囊内容物;最后将胶囊内容物灌装进空胶囊得到米非司酮胶囊。本发明通过添加自制的增溶 |
---|---|
Bibliography: | Application Number: CN202210073280 |