Simultaneous quantification of gene expression in user-defined regions of cross-sectional tissue

• Main Authors: BEE JOSEPH M, SORG KATHRIN, MERRITT CHRIS, WARREN CHARLES, CROWDER SCOTT, DUNAWAY DWAYNE L, JIANG JING
• Format: Patent
• Language: Chinese; English
• Published: 15.04.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The present invention relates to simultaneous quantification of gene expression in user-defined regions of cross-sectional tissue. The present invention relates, inter alia, to probes, compositions, methods and kits for simultaneous, multiplex detection and quantification of protein and/or nucleic acid expression in user-defined tissue regions, user-defined cells, and/or user-defined intracellular subcellular structures. 本发明涉及在横切面组织的用户定义区域中的基因表达的同时定量。本发明尤其涉及探针、组合物、方法和试剂盒，其用于同时、多重检测和定量用户定义的组织区域、用户定义的细胞，和/或用户定义的细胞内亚细胞结构中的蛋白和/或核酸表达。