Preparation method of pentenedioic acid diester

• Main Authors: QIU LI, CAI GUANGWEI, ZHANG GANG, DENG JIALUN, LI XIANG, LI ZIYONG, LIU XIAOCHENG
• Format: Patent
• Language: Chinese; English
• Published: 15.04.2022
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention relates to the field of fine chemical engineering, in particular to a preparation method of pentenedioic acid diester. The invention relates to a preparation method of pentenedioic acid diester, which comprises the following steps: by taking malonic acid diester and halomethane as raw materials, carrying out substitution reaction under the condition of alkali action, and then carrying out decarboxylation and esterification reaction to prepare the pentenedioic acid diester with a structural formula as shown in a compound (IX). The preparation method of the pentenedioic acid diester is mild in reaction condition, easy to operate and safe in process. The preparation method is mild in reaction condition, easy to operate and safe in process. 本发明涉及精细化工领域，具体涉及一种戊烯二酸二酯的制备方法。戊烯二酸二酯的制备方法，以丙二酸二酯和卤代甲烷为原料，在碱作用条件下进行取代反应，再经脱羧、酯化反应制备戊烯二酸二酯，结构式见化合物(Ⅸ)。该方法反应条件温和、易操作，工艺安全的戊烯二酸二酯的制备方法。该制备方法反应条件温和、易操作，工艺安全。