Preparation method of water-soluble low-crosslinking polyglutamic acid

• Main Authors: XU ZEPING, LIU HAIYU, ZHANG XINQING, HE FUMING, TIAN JIEWEI, YANG CHUANLUN, CHAO JIN, GAO BAOJUN
• Format: Patent
• Language: Chinese; English
• Published: 25.03.2022
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; GENERAL PROCESSES OF COMPOUNDING; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS; WORKING-UP

The invention belongs to the field of fine chemicals, particularly relates to the field of cosmetics, and provides a preparation method of water-soluble low-crosslinking polyglutamic acid, which comprises the following steps: by taking low-molecular-weight polyglutamic acid as a raw material, adding a certain amount of crosslinking agent to obtain colloidal gel which is incompletely reacted, then carrying out low-temperature reaction, adding water, homogenizing, filtering, washing and drying to obtain the water-soluble low-crosslinking polyglutamic acid. And then adding a stabilizer and a preservative to obtain the water-soluble low-crosslinking polyglutamic acid. The prepared low-crosslinking polyglutamic acid is stable in property, not only retains the advantages of polyglutamic acid, but also can be stably compounded with carbomer, and the method is simple and easy to operate. 本发明属于精细化学品领域，具体涉及化妆品领域，提供了一种水溶性低交联聚谷氨酸的制备方法，包括以下步骤：以低分子量聚谷氨酸为原料，加入一定量的交联剂后获得反应不完全的胶体状凝胶，再进行低温反应后加水均质，然后加入稳定剂、防腐剂，即为水溶性低交联聚谷氨酸。本发明制得