Magnetic field/temperature dual-response hydrogel as well as preparation method and application thereof

• Main Authors: CUI YUXIN, LIANG YANBO, DENG ZILI, XIU HUIJUAN, ZHAO HAIZHI, LI NA, LI JINBAO, DU XIAOYUN
• Format: Patent
• Language: Chinese; English
• Published: 22.03.2022
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS; WORKING-UP

The invention discloses magnetic field/temperature dual-response hydrogel and a preparation method and application thereof.The preparation method includes the steps that Fe3O4 is added into a stable layer pre-polymerization solution through a blending method, the Fe3O4 is subjected to ultrasonic blending with polyvinyl alcohol with extremely high polarity, and the water solubility and the film-forming property of the polyvinyl alcohol are utilized, so that the Fe3O4 is evenly dispersed into the stable layer pre-polymerization solution; then carrying out freeze-thaw cycle on a microgelation product obtained by sequentially pouring the stable layer pre-polymerization liquid and the swelling layer pre-polymerization liquid, so that the microgelation product is completely gelated; the completely gelatinized magnetic field/temperature double-response hydrogel is soaked in sodium sulfate, the internal crosslinking density of the gel is improved through the salting-out effect, and the magnetic field/temperature doub