Synthetic lipids for mRNA delivery

Provided is a method of treating a lipoprotein metabolic disorder or cardiovascular disease in a human comprising administering to a subject in need thereof a lipid-like nanoparticle comprising a lipid, CRISPR/Cas9 mRNA, and a single guide RNA (sgRNA). 提供了治疗人类脂蛋白代谢障碍或心血管疾病的方法，其包括给予需要它的受试者包含脂质、CRISPR...

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Bibliographic Details
Main Authors WANG MIN, XU QIUYUN
Format Patent
LanguageChinese
English
Published 11.03.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided is a method of treating a lipoprotein metabolic disorder or cardiovascular disease in a human comprising administering to a subject in need thereof a lipid-like nanoparticle comprising a lipid, CRISPR/Cas9 mRNA, and a single guide RNA (sgRNA). 提供了治疗人类脂蛋白代谢障碍或心血管疾病的方法，其包括给予需要它的受试者包含脂质、CRISPR/Cas9 mRNA和单引导RNA(sgRNA)的类脂纳米颗粒。
Bibliography:Application Number: CN20208054813