No-rinse chemical foam containing brimonidine, and use thereof in the treatment of rosacea

• Main Authors: NADAU-FOURCADE KARINE, BUGE JEANRISTOPHE
• Format: Patent
• Language: Chinese; English
• Published: 11.02.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to a no-rinse chemical foam containing brimonidine, and use thereof in the treatment of rosacea, specially, to a self-foaming composition containing brimonidine, for a no-rinse topical application, comprising: at least one intermediate composition B comprising a gas-generating agent; at least one intermediate composition A comprising an agent for activating the gas-generating agent; and brimonidine or one of the pharmaceutically acceptable salts thereof contained in at least one of said intermediate compositions A and B. The invention also relates to a kit or a single container comprising a plurality of compartments containing such a composition. 本发明涉及含溴莫尼定的免冲洗化学泡沫及其在治疗红斑痤疮中的用途，特别地含有溴莫尼定的自发泡组合物，其旨在用于免冲洗局部施用，其包含：-至少一种中间组合物B，其包含气体发生剂，-至少一种中间组合物A，其包含用于气体发生剂的激活剂；-溴莫尼定或其在药学上可接受的盐中的一种，其被包含在所述中间组合物A和B中的至少一种中。本发明还涉及包含这种组合物的试剂盒或具有多隔室的单个容器。