SYSTEMS AND METHODS FOR LIQUID INJECTION

• Main Authors: ABRAMSON ALEX, JESPERSEN MIKKEL, LU XIAOYA, LEY MIKKEL WENNEMOES HVITFELD, TRAVERSO CARLO, FERGUS ANDREW, LANGER ROBERT, POULSEN METTE, FREDERIKSEN MORTEN, WATER JORRIT JEROEN, MOURIDSEN BRIAN, WINDUM JESPER, JENSEN BRIAN
• Format: Patent
• Language: Chinese; English
• Published: 28.01.2022
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self- righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject) such as a liquid pharmaceutical agent. In some cases, upon contact of the tissue with the tissue engaging surface of the