Marker group and early diagnosis kit for rheumatoid-arthritis intestinal microorganisms

• Main Authors: DENG YUSHENG, HAN LIJUAN
• Format: Patent
• Language: Chinese; English
• Published: 07.01.2022
• Subjects: BEER; BIOCHEMISTRY; CALCULATING; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPUTING; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; COUNTING; ENZYMOLOGY; HANDLING RECORD CARRIERS; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PRESENTATION OF DATA; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROCESSES USING MICROORGANISMS; RECOGNITION OF DATA; RECORD CARRIERS; SPIRITS; VINEGAR; WINE

The invention discloses a marker group and early diagnosis kit for rheumatoid-arthritis intestinal microorganisms. The marker group for the rheumatoid-arthritis intestinal microorganisms comprises 43 different microorganism combinations, and the rheumatoid-arthritis enteric microorganism combinations can be applied to risk estimation of rheumatoid arthritis. The early diagnosis kit of rheumatoid arthritis comprises a probe and/or a primer aiming at the biomarker group, and the kit is proved to have higher detection rate and higher accuracy, can be used for comprehensively embodying the difference condition of intestinal microorganisms of patients with rheumatoid arthritis, can be used for early detecting the rheumatoid arthritis, time is won for the patients, treatment is started as soon as possible, and the clinical treatment effect is improved. 本发明公开一种类风湿关节炎肠道微生物的标志物组及早期诊断试剂盒，类风湿关节炎肠道微生物的标志物组包括43种差异微生物组合，该类风湿关节炎肠道微生物组合可用于类风湿关节炎风险预估。该类风湿关节炎的早期诊断试剂盒是包括针对上述生物标记物组的探针和/或引物，经验证该试剂盒具有较高的检出率和较高的准确度，可以综合地体现类风湿关节炎患者的