USE OF CO-CRYSTALS OF TRAMADOL AND CELECOXIB FOR TREATING PAIN WHILE REDUCING THE ABUSE LIABILITY OF TRAMADOL

• Main Authors: PLATA-SALAMAN CARLOS-RAMON, ENCINA-GARCIA GREGORIO-JOSE
• Format: Patent
• Language: Chinese; English
• Published: 21.12.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to the use of co-crystals of tramadol and celecoxib for the treatment of pain, preventing the risk of an addiction to tramadol, for the treatment of pain while reducing the abuse liability of tramadol, for the treatment of pain also reducing an incidence of addiction to tramadol, for the treatment of pain preventing an addiction to tramadol, for the treatment of pain in a patient with an addiction to tramadol or the risk of it, for the treatment of pain and inhibiting, delaying, reducing or reversing an addiction to tramadol or for treatment of pain and reducing an incidence of addiction to tramadol. 本发明涉及曲马多和塞来昔布的共晶体用于治疗疼痛，预防曲马多成瘾风险，用于治疗疼痛同时降低曲马多的滥用倾向，用于治疗疼痛并降低曲马多成瘾发生率，用于预防曲马多成瘾的疼痛治疗，用于治疗曲马多成瘾或有此风险的患者的疼痛，用于治疗疼痛并抑制、延迟、减轻或逆转曲马多成瘾或用于治疗疼痛并降低曲马多成瘾的发生率的用途。