Stable small-peptide chelated calcium as well as preparation method and application thereof

• Main Authors: ZHANG QINQIANG, GUO BAOZHEN, ZHAI TING, SHEN CAIQIN, WANG YONG, GUO SIHUA
• Format: Patent
• Language: Chinese; English
• Published: 21.12.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The invention discloses stable small-peptide chelated calcium and a preparation method and application thereof. The preparation method comprises the steps: firstly, preparing a small-peptide mixed solution by taking pig bones as raw materials, then, adding a calcium chloride solution into the small-peptide mixed solution, and carrying out a reaction with stirring, so as to obtain a small-peptide chelated calcium solution; adding sodium alginate into the small-peptide chelated calcium solution, carrying out stirring until the sodium alginate is completely dissolved, then, adding a superfine calcium carbonate suspension, carrying out uniform stirring and mixing to obtain a premix, then, dropwise adding the premix into a D-glucolactone solution, continuously to perform stirring until uniform sol is formed, carrying out sealing and standing, and carrying out filtering to obtain microspheres; and finally, dissolving polyvinyl alcohol in water, then, adding carboxymethyl chitosan and the microspheres, carrying out