Preparation method and application of radix ranunculi ternati multi-arm phospholactone substance with breast cancer targeting structure
The invention relates to a preparation method and application of a radix ranunculi ternati multi-arm phospholactone substance with a breast cancer targeting structure. The preparation method comprises the following steps of drying, grinding and sieving cleaned radix ranunculi ternati, adding into wa...
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Main Authors | , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
17.12.2021
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Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to a preparation method and application of a radix ranunculi ternati multi-arm phospholactone substance with a breast cancer targeting structure. The preparation method comprises the following steps of drying, grinding and sieving cleaned radix ranunculi ternati, adding into water, carrying out enzymolysis for 3 hours by utilizing cellulose hydrolase under stirring, adding pectinase and papain, carrying out enzymolysis for 2 hours, adding amylase, carrying out enzymolysis for 1 hour, filtering, and adding folic acid, chitosan sodium alginate and a phenylboronic acid solution into the filtrate, stirring and reacting in a water bath kettle at 80-100 DEG C for 10-15 hours, carrying out reduced pressure distillation on the obtained mixed solution for 10 hours, and freeze-drying the obtained liquid to obtain the multi-arm phospholactone substance. The radix ranunculi ternati is used as a raw material, a biological active substance radix ranunculi ternati lactone is obtained by utilizing a bio |
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Bibliography: | Application Number: CN202111136114 |