TRIAMTERENE OR NOLATREXED FOR USE IN TREATMENT OF PHENYLKETONURIA

• Main Authors: REIG BOLAÑO NURIA, SIGNORILE LUCA, PERICOT MOHR GAL LA, INSA BORONAT RAUL INSA BORONAT, HUERTAS GAMBIN OSCAR, ESTEVA GRAS SANTIAGO, FERRE FERRE AILEEN
• Format: Patent
• Language: Chinese; English
• Published: 30.11.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a compound selected from the group consisting of nolatrexed, triamterene, sultopride and hydrastinine or a pharmaceutically acceptable salt thereof, preferably triamterene, nolatrexed or a pharmaceutically acceptable salt thereof, and to the combination of said compounds with other active ingredients, to the use of said compound or its combinations in the manufacture of a medicament for the treatment or prevention of said diseases and to a method of treating and/or preventing by administration of said compound or its combinations. 本发明涉及用于治疗和/或预防苯丙酮尿症的选自以下的化合物：诺拉曲塞、氨苯蝶啶、舒托必利和白毛茛分碱或其药学上可接受的盐，优选地氨苯蝶啶、诺拉曲塞或其药学上可接受的盐，以及所述化合物与其他活性成分的组合，涉及所述化合物或其组合在制造用于治疗或预防所述疾病的药物中的用途，并且涉及通过施用所述化合物或其组合来进行治疗和/或预防的方法。