Medical polymer material as well as preparation method and application thereof

• Main Author: CAO SHUJUN
• Format: Patent
• Language: Chinese; English
• Published: 26.11.2021
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS

The invention discloses a medical polymer material and a preparation method and application thereof. The preparation method comprises the steps of preparing amido modified polytetrafluoroethylene, preparing graphene oxide grafted polytetrafluoroethylene and loading titanium dioxide on a polytetrafluoroethylene material. Under the action of ultrasonic waves, polytetrafluoroethylene is activated, the surface of polytetrafluoroethylene can be grafted with PAMAM-NH2, the PAMAM-NH2 is a high-molecular dendritic polymer, graphene oxide contains a large amount of carboxyl and epoxy groups, NH2 on the surface of PAMAM-NH2 can react with the functional group in graphene oxide, titanium dioxide is loaded on the surface of the material through a sol-gel method, and therefore, the bio-compatibility of the material is improved. 本发明公开了一种医用高分子材料及其制备方法和应用，包括制备胺基改性聚四氟乙烯、制备氧化石墨烯接枝聚四氟乙烯以及聚四氟乙烯材料负载二氧化钛，本发明在超声波的作用下，使聚四氟乙烯活化，能够实现在聚四氟乙烯的表面接枝PAMAM-NH2，PAMAM-NH2是一种高分子树枝状聚合物，同时氧化石墨烯中含有大量的羧基和环氧基，PAMAM-NH2表面的NH2能与氧化石墨烯中的官能团进行反应，再通过溶胶凝胶法