Anti-human SEMA4D antibody as well as preparation method and application thereof
The invention relates to the technical field of biology, in particular to an anti-human SEMA4D antibody and a preparation method and application thereof. The anti-human SEMA4D antibody can be used for specifically recognizing an SEMA4D protein; the anti-human SEMA4D antibody comprises a first antibo...
Saved in:
Main Authors | , , , , , , , , |
---|---|
Format | Patent |
Language | Chinese English |
Published |
02.11.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The invention relates to the technical field of biology, in particular to an anti-human SEMA4D antibody and a preparation method and application thereof. The anti-human SEMA4D antibody can be used for specifically recognizing an SEMA4D protein; the anti-human SEMA4D antibody comprises a first antibody or a second antibody; the first antibody comprises any one of amino acid sequences as shown in SEQ ID NO: 1-SEQ ID NO: 37, the second antibody sequence meets at least one of the following conditions: a heavy chain amino acid sequence comprises any one of amino acid sequences as shown in SEQ ID NO: 38-SEQ ID NO: 42, a light chain amino acid sequence comprises any one of amino acid sequences as shown in SEQ ID NO: 43-SEQ ID NO: 47, and a plurality of anti-human SEMA4D antibodies with higher affinity are obtained. An early detection and diagnosis marker and a treatment target are provided, and a basis is provided for combined antibody medication and tumor control.
本申请涉及生物技术领域,尤其涉及抗人SEMA4D抗体及其制备方法和应用。所述抗人SEMA4D抗体能特异 |
---|---|
Bibliography: | Application Number: CN202110860942 |