Estramustine formulations with improved pharmaceutical properties
PCT No. PCT/EP95/03438 Sec. 371 Date May 6, 1996 Sec. 102(e) Date May 6, 1996 PCT Filed Sep. 1, 1995 PCT Pub. No. WO96/09072 PCT Pub. Date Mar. 28, 1996The present invention provides a pharmaceutical composition comprising an estramustine derivative and a cyclodextrin, particularly in the manufactur...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
13.11.1996
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | PCT No. PCT/EP95/03438 Sec. 371 Date May 6, 1996 Sec. 102(e) Date May 6, 1996 PCT Filed Sep. 1, 1995 PCT Pub. No. WO96/09072 PCT Pub. Date Mar. 28, 1996The present invention provides a pharmaceutical composition comprising an estramustine derivative and a cyclodextrin, particularly in the manufacture of a medicament suitable for the oral administration of an estramustine derivative to a patient suffering from a tumor. Estramustine derivatives according to the invention are, for example, compounds of general formula (I) (I) wherein R is in which R1 is C1-C4 alkyl and n is 0, 1 or 2, and the pharmaceutically acceptable salts thereof. |
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Bibliography: | Application Number: CN19951090926 |