Method for preparing nano-hydroxyapatite composite silane film on surface of medical magnesium matrix

• Main Authors: LIU BING, LYU YUPENG, SONG ZHIGANG, XIAO GUIYONG
• Format: Patent
• Language: Chinese; English
• Published: 29.10.2021
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMICAL SURFACE TREATMENT; CHEMISTRY; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATIONOR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY IONIMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; COATING MATERIAL WITH METALLIC MATERIAL; COATING METALLIC MATERIAL; DIFFUSION TREATMENT OF METALLIC MATERIAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION INGENERAL; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THESURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION

The invention belongs to the field of surface modification of biomedical metal materials, and relates to a method for preparing a nano-hydroxyapatite composite silane film on the surface of a medical magnesium matrix. The method comprises the following steps: sequentially mixing deionized water with absolute ethyl alcohol, gamma-(2, 3-epoxypropoxy) propyltrimethoxysilane and tetraethoxysilane, regulating the pH value to 4.500-5.500 by using glacial acetic acid, then hydrolyzing for 12-24 hours, and preparing a silane hydrolysis solution; taking 0.05-0.2 g of nano hydroxyapatite particles, and dispersing the nano hydroxyapatite particles into the absolute ethyl alcohol; mixing 15ml of the hydrolyzed silane solution with 5ml of the nano-hydroxyapatite solution, and carrying out ultrasonic dispersion for 10 minutes; and soaking hydroxylated pure magnesium or magnesium alloy in a hydrolyzed silane solution for 1-5 minutes, then performing pulling out at a constant speed, and performing heating at 80-150 DEG C for