FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS

Phospholipid-polymer-aromatic conjugates comprising binding ligands, liposome compositions including the phospholipid-polymer-aromatic conjugates, and binding ligands having an affinity for misfolded proteins are described. The liposomal compositions may be useful for the imaging of misfolded and/or...

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Bibliographic Details
Main Authors MEDICI CARLO, ANNAPRAGADA ANANTH V, NELSON PATRICK, TANIFUM ERIC A
Format Patent
LanguageChinese
English
Published 22.10.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Phospholipid-polymer-aromatic conjugates comprising binding ligands, liposome compositions including the phospholipid-polymer-aromatic conjugates, and binding ligands having an affinity for misfolded proteins are described. The liposomal compositions may be useful for the imaging of misfolded and/or aggregated proteins. 描述了磷脂-聚合物-芳烃缀合物(包含结合配体)、脂质体组合物(包含磷脂-聚合物-芳烃缀合物)和对错误折叠的蛋白质具有亲和力的结合配体。脂质体组合物可用于对错误折叠和/或聚集的蛋白质进行成像。
Bibliography:Application Number: CN202080018762