Marker and detection kit for cardia cancer screening

• Main Authors: WANG LIDONG, MA LINLIN, FAN ZONGMIN, LI ZHIQIANG, LEI LINGLING, YANG MIAOMIAO, WANG PANPAN, WEI MENGXIA, ZHONG KAN, HU JINGFENG, HAN WENLI, SONG XIN, ZHAO XUEKE, XU RUIHUA
• Format: Patent
• Language: Chinese; English
• Published: 28.09.2021
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention belongs to the technical field of medical biology, and particularly discloses a marker and a detection kit for cardia cancer screening. The marker for screening the cardia cancer, which is provided by the invention, is at least one of Xanthurenic Acid and 2-Hydroxy-2-methylbutyric acid, and a detection reagent of the marker can be used for preparing a product for screening the cardia cancer. The invention also provides the kit for screening cardia cancer, the kit contains a detection reagent for detecting the marker, and the detection reagent is a reagent for detecting the marker in a sample through chromatography-mass spectrometry or chromatography-mass spectrometry. The cardia cancer can be effectively detected by detecting the expression levels of Xanthurenic Acid and 2-Hydroxy-2-methylbutyric acid in human serum, the detection sensitivity reaches up to 94.3%, the specificity reaches 97.0%, and the kit can be used for large-scale screening of asymptomatic crowds in a cardia cancer high-incide