THIENO[3,2-B]PYRIDINE DERIVATIVES AS UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE

Disclosed herein is a compound of Formula (I), as described herein, and pharmaceutically acceptable salts thereof. Also disclosed herein are compositions and the use of such compositions in methods of treating a variety of diseases and conditions, in particular Krabbe's Disease (KD) and Metachr...

Full description

Saved in:
Bibliographic Details
Main Authors MANIAR SACHIN, CHOI YONG-MI, BARKER JR ROBERT H, THURAIRATNAM SUKANTHINI, MAKINO ELINA, JIANG JUE, ANGELASTRO MICHAEL, MUNSON MARK, CROMWELL MARY A, HIRTH BRADFORD, MUSICK KWON YON, PRIBISH JAMES, LIM SUNG
Format Patent
LanguageChinese
English
Published 21.09.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Disclosed herein is a compound of Formula (I), as described herein, and pharmaceutically acceptable salts thereof. Also disclosed herein are compositions and the use of such compositions in methods of treating a variety of diseases and conditions, in particular Krabbe's Disease (KD) and Metachromatic leukodystrophy (MLD). 本文公开了如本文所述的式(I)的化合物及其药学上可接受的盐。本文还公开了组合物和此类组合物在治疗多种疾病和病症、特别是克拉伯氏病(KD)和异染性脑白质营养不良(MLD)的方法中的用途。
Bibliography:Application Number: CN201980076707