Biogel for treating refractory ulcer and preparation method thereof

• Main Authors: WANG LI, GE FENG, HUANG XIAODAN, OU QING, DING GAOMING, HUANG JUN, JU WENDONG, ZHENG MINMIN
• Format: Patent
• Language: Chinese; English
• Published: 17.09.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to a biogel for treating refractory ulcer and a preparation method thereof, and the biogel is prepared by mixing materials comprising mechanically collected platelets or artificially separated and concentrated platelets, cryoprecipitates, a 10% calcium chloride solution and thrombin freeze-dried powder,the dosage ratio of mechanically collected platelets or artificially separated and concentrated platelets to the cryoprecipitate to the 10% calcium chloride solution to the thrombin freeze-dried powder is (50mL-67 mL): (20mL-30 mL): (3mL-5 mL): (4000-6000 U). The biogel can effectively treat refractory ulcers, and the raw materials are easy to obtain, safe, reliable and easy to prepare. 本发明涉及用于治疗难治性溃疡的生物凝胶及其制备方法，该生物凝胶由包含机采血小板或人工分离浓缩血小板、冷沉淀、10％氯化钙溶液和凝血酶冻干粉的材料混合制成，机采血小板或人工分离浓缩血小板、冷沉淀、10％氯化钙溶液和凝血酶冻干粉的用量比例为(50mL～67mL)：(20mL～30mL)：(3mL～5mL)：(4000U～6000U)。该生物凝胶能够有效治疗难治性溃疡，并且原料易得，安全可靠，容易制备。