NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO

• Main Authors: FEURA EVAN SCOTT, MALONEY SARA ELIZABETH, YANG LEI, SCHOENFISCH MARK H, AHONEN MONA JASMINE R, KIM HYEONGSIK
• Format: Patent
• Language: Chinese; English
• Published: 10.09.2021
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; THEIR PREPARATION OR CHEMICAL WORKING-UP

Several embodiments of NO releasing structures are disclosed. In some embodiments, the structures are covalently modified to store and release nitric oxide. Some embodiments pertain to methods of making and use of these structures. The covalently modified polymer structures may be tailored to release nitric oxide in a controlled manner and are useful for treatment of various medical conditions. 公开了NO释放型结构的若干实施例。在一些实施例中，对所述结构进行共价修饰以储存和释放一氧化氮。一些实施例涉及制备和使用这些结构的方法。经共价修饰的聚合物结构可以被调整为以受控方式释放一氧化氮并且可用于治疗各种医学病状。