Test strip for early screening of cardia adenocarcinoma of high-risk population

• Main Authors: WANG LIDONG, LI AILI, LUO HONG, LI ZHIQIANG, LEI LINGLING, YANG MIAOMIAO, WANG PANPAN, GUO GUIZHOU, WEI MENGXIA, ZHONG KAN, HU CHUANSONG, HU JINGFENG, HAN WENLI, LI CHENGKUAN, SONG XIN, ZHAO XUEKE, XU RUIHUA
• Format: Patent
• Language: Chinese; English
• Published: 17.08.2021
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention belongs to the technical field of medical biology, and discloses a test strip for early screening of cardia adenocarcinoma of high risk population, the test strip comprises a combination pad and a chromatography pad, the combination pad is coated with a capture antibody, the capture antibody is a mixture of a GAGE12B antibody A, an AGPAT4 antibody A and a P2RX4 antibody A, and the GAGE12B antibody A, the AGPAT4 antibody A and the P2RX4 antibody A all have detectable markers; three detection lines and a quality control line are arranged on the chromatographic pad, and detection antibodies fixed by the three detection lines are respectively a GAGE12B antibody B, an AGPAT4 antibody B and a P2RX4 antibody B; and rabbit anti-mouse IgG is fixed on the quality control line. The test strip provided by the invention can rapidly detect GAGE12B, AGPAT4 and P2RX4 in human serum, realizes joint detection of three tumor markers, can effectively detect cardia adenocarcinoma according to a detection result, and