PYRROLO-PYRIDAZINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the preparation, pharmaceutical composition...

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Main Authors NIROGI RAMAKRISHNA, MOHAMMED ABDUL RASHEED, SHINDE ANIL KARBHARI, SUBRAMANIAN RAMKUMAR, RAVELLA SRINIVASA RAO, JASTI VENKATESWARLU
Format Patent
LanguageChinese
English
Published 23.07.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the preparation, pharmaceutical composition and the use of such compounds. 本发明涉及作为毒蕈碱型M1受体正向别构调节剂(M1 PAM)的式(I)化合物或者其同位素形式、立体异构体、互变异构体或其可药用盐。本发明描述了此类化合物的制备、药物组合物和用途。
Bibliography:Application Number: CN20198080853