PROCESS FOR PREPARING FATTY ACID CHLORIDES AND N-ACYL AMINO ACID SALTS

• Main Authors: SONI JIGNALKUMAR NURPESHKUMAR, PATIL RAJU DAYARAM, CONTRACTOR PRERAK RAJENDRAKUMAR
• Format: Patent
• Language: Chinese; English
• Published: 23.07.2021
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention relates to a process for preparing fatty acid chlorides. In a subsequent step, the fatty acid chlorides can be used to prepare N-acyl amino acid salts. The process comprises the formation of a fatty acid chloride in an amine catalyzed reaction of a fatty acid with phosphorous trichloride, thionyl chloride or phosgene, preferably thionyl chloride. The process for preparing N-acyl amino acid salts further comprises the reaction of the fatty acid chloride with an amino acid or an amino ethane sulfonic acid. 本发明涉及制备脂肪酰氯的方法。在随后的步骤中，脂肪酰氯可用于制备N-酰基氨基酸盐。所述方法包括在脂肪酸与三氯化磷、亚硫酰氯或光气，优选亚硫酰氯的胺催化反应中形成脂肪酰氯。制备N-酰基氨基酸盐的方法还包括使脂肪酰氯与氨基酸或氨基乙烷磺酸反应。