SAFE AND EFFECTIVE METHOD OF TREATING ULCERATIVE COLITIS WITH ANTI-IL12/IL23 ANTIBODY

Described are methods and compositions for clinical proven safe and effective treatment of ulcerative colitis, particularly moderately to severely active ulcerative colitis in patients who have had an inadequate response to or are intolerant of a conventional or existing therapy by intravenous and/o...

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Main Authors STRAUSS RICHARD, SHIELDS-TUTTLE KIMBERLY, ADEDOKUN OMONIYI, MARANO COLLEEN, JOHANNS JEWEL, ZHANG HENG, O'BRIEN CHRISTOPHER, LEE KEVIN
Format Patent
LanguageChinese
English
Published 23.07.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Described are methods and compositions for clinical proven safe and effective treatment of ulcerative colitis, particularly moderately to severely active ulcerative colitis in patients who have had an inadequate response to or are intolerant of a conventional or existing therapy by intravenous and/or subcutaneous administration of an anti-IL-12/IL-23p40 antibody. 本发明描述了用于通过静脉内和/或皮下施用抗IL-12/IL-23p40抗体为对常规疗法或现有疗法应答不足或耐受不良的患者提供临床证实安全且有效的治疗溃疡性结肠炎特别是中度至重度活动性溃疡性结肠炎的方法和组合物。
Bibliography:Application Number: CN201980077285