Preparation method of taste-masking slow-release tilmicosin premix

The invention discloses a preparation method of a taste-masking slow-release tilmicosin premix, which comprises the following steps: a, obtaining raw materials including tilmicosin, a carrier material, a coating slow-release material, a corrigent and a tissue improver for later use; b, uniformly mix...

Full description

Saved in:
Bibliographic Details
Main Authors ZHAN PENGFEI, YANG BIAO, YANG CAIMEI, ZENG XINFU, LIU JINSONG
Format Patent
LanguageChinese
English
Published 23.07.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention discloses a preparation method of a taste-masking slow-release tilmicosin premix, which comprises the following steps: a, obtaining raw materials including tilmicosin, a carrier material, a coating slow-release material, a corrigent and a tissue improver for later use; b, uniformly mixing the tilmicosin, the carrier material and the corrigent, firstly wetting with water in an extruder, extruding and granulating, further performing shot blasting and shaping through a shot blasting machine to prepare pellets, and controlling the water content of the pellets within 5%; and c, heating and melting the inner-layer coating sustained-release agent, adding the tissue improver to prepare an inner-layer coating solution, and keeping the temperature at 80-85 DEG C. The tilmicosin premix disclosed by the invention is prepared through a double-layer coating slow-release taste-masking and corrective technology to achieve a good masking effect on the bitter taste of tilmicosin, meanwhile, the tilmicosin premix
Bibliography:Application Number: CN202110003896