Sodium ozagrel for injection and preparation method thereof

• Main Authors: WEI XUEWEN, DAI HONGXU, PENG QI, SU LING
• Format: Patent
• Language: Chinese; English
• Published: 06.07.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses sodium ozagrel for injection. Raw materials in per thousand bottles include the following components in parts by weight: 20g of sodium ozagrel and water for injection, wherein the volume of the water for injection is adjusted to 1000ml. By reducing addition of auxiliary materials, inevitable system pollution in the process of adding the auxiliary materials is reduced, meanwhile, process steps are also simplified, and bacterial endotoxin detection of mannitol does not need to be carried out in production. In one aspect, the invention further provides a preparation method of the ozagrel sodium for injection; a preparation process is adjusted and optimized, so that the solubility of the ozagrel sodium for injection is improved, and the appearance with a relatively good shape is obtained while the purity of the ozagrel sodium for injection is improved. The sodium ozagrel for injection and the preparation method of the sodium ozagrel are used for solving the technical problems that an exist