Zangyinchen extract, and preparation method and application thereof

• Main Authors: LIU MIN, GENG HAIMING, CHEN HONGWEI, WANG KAI, DI YICHAO
• Format: Patent
• Language: Chinese; English
• Published: 29.06.2021
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The invention puts forward a Zangyinchen extract, a preparation method thereof, a preparation with a lipid-lowering function, a preparation with a sugar-lowering function, the purposes of a Zangyinchen extract and the preparations, and a medicine composition containing the Zangyinchen extract and the preparations. The Zangyinchen extract contains swertiamarin, mangiferin, gentiopicroside, sweroside, herba swertiae alcoholic glycoside and methylswertianin at a mass ratio of (1-5): (10-120): (1-5): (5-12): (5-30): (5-20). The Zangyinchen extract disclosed by the invention has a good lipid-lowering and sugar-lowering function, can obviously improve absorption of glucose in an insulin-resistance cell model and eliminate lipid accumulation in the insulin-resistance cell model, and has an important theoretical research and clinical application value. 本发明提出了藏茵陈提取物及其制备方法、具有降脂作用的制剂、具有降糖作用的制剂、藏茵陈提取物和制剂的用途及含有其的药物组合物，所述藏茵陈提取物含有獐牙菜苦苷、芒果苷、龙胆苦苷、当药苷、当药醇苷和甲基当药宁，其中，所述獐牙菜苦苷、芒果苷、龙胆苦苷、当药苷、当药醇苷和甲基当药宁的质量比为(1～5)：(10～120)：(1～5)：(5～12