METHODS FOR RANKING AND/OR SELECTING TUMOR-SPECIFIC NEOANTIGENS

• Main Authors: KAYSER SIMONE, FELDHAHN MAGDALENA, HADASCHIK DIRK, MENZEL MORITZ, ARMEANU-EBINGER SORIN, BISKUP DIRK, BATTKE FLORIAN, BISKUP SASKIA, KYZIRAKOS CHRISTINA -FEGER
• Format: Patent
• Language: Chinese; English
• Published: 25.06.2021
• Subjects: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; PHYSICS

The present invention relates to the ranking/selection of tumor-specific neoantigens of a subject having cancer. The present invention also provides methods using the ranked/selected tumor-specific neoantigens in, for example, the treatment or prevention of cancer. Ranked and selected neoantigens may be used as biomarkers in the diagnosis, monitoring and/or prognosis of tumor diseases. 本发明涉及患有癌症的受试者的肿瘤特异性新抗原的分级/选择。本发明还提供了在例如癌症的治疗或预防中使用分级/选择的肿瘤特异性新抗原的方法。分级和选择的新抗原可以在肿瘤疾病的诊断、监测和/或预后中用作生物标记物。