Methods of reducing need for peripheral arterial revascularization in statin-treated subject

• Main Authors: GRANOWITZ CRAIG, PHILIP SEPHY
• Format: Patent
• Language: Chinese; English
• Published: 04.06.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

In various embodiments, the present disclosure provides methods of diagnosing a need for peripheral arterial revascularization and/or reducing a need for peripheral arterial revascularization in a subject by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof. 在多种实施方案中，本公开提供了诊断受试者对外周动脉血运重建的需求和/或通过向受试者施用包含约1g至约4g的二十碳五烯酸乙酯或其衍生物的药学上可接受的组合物来减少受试者对外周动脉血运重建的需求的方法。